LAB NEWS
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Straight out of eLife
July
Allosteric activation of the co-receptor BAK1 by the EFR receptor kinase initiates immune signaling
Congrats to Henning Mühlenbeck and Yuko Tsutsui from the Lemmon Lab!
New Paper in Structure!
Congrats to the Ferguson Lab on their latest paper Structural insights into the role and targeting of EGFRvIII
June
“These findings suggest new avenues for EGFRvIII targeting in GBM.”
April 29 - 30, 2024
Excellent retreat for the Department of Pharmacology at Mt. Snow this week. Inspiring to hear the excellent work of our terrific postdocs and students. And thanks to Roy Herbst for a fantastic keynote.
April 2024 - Congratulations to Bowei Deng and Kyle Misquitta on both passing their qualifying exams with flying colors this week!
Check it out in Cell Reports!
December 2023 “Using single-particle tracking and imaging in a study supported by our division, Dr. Krishna Mudumbi et al. revealed insights into the interactions that stabilize epidermal growth factor receptor (EGFR) assemblies in cell membranes.” - NCI Division of Cancer Biology
New paper out in Nature Communications!
Oct. 4, 2023
Check out this collaboration here with Courtney Smith and Alice Li on the “glycoproteomic landscape and structural dynamics of TIM family”.
Check out Henning Mühlenbeck’s preprint in BioRvix on non-catalytic signaling mechanisms of plant RKs! August 25, 2023
Congrats to Krishna!
Krishna Mudumbi, PhD was selected for the Intersections Science Fellows Symposium (ISFS) October 2023!
Check out their wesbite here https://www.intersectionssciencefellows.com/fellows-associates
Lucy is at it again
July 2, 2023
Undergrand Lucy Kim presented her first poster at the Yale Cancer Center trainee symposium.
RM1 Awarded!
June 28, 2023
Congrats to Dr. Kathryn Ferguson and the team on receiving the grant from NIGMS to understand membrane proteins in their natural environment! Read the article here
May 30, 2023
Great job by undergrad Lucy Kim presenting our work at today's Yale West Campus’ All Points West Symposium!
Congratulations to Zaritza Petrova as first author on her paper in Nature Communications!
May 5, 2023
Check out this collaborative study of ALK in neuroblastoma here
Preprint out on BioRxiv!
Check out Krishna’s preprint on using single particle tracking and other imaging approaches to understand how different interactions stabilize EGFR dimers and higher-order oligomers!
Annual YCBI Retreat at Mount Snow, Vermont
February 2 & 3, 2023 — The Cancer Biology Institute celebrated good company and collaborated together over exciting research at a long overdue retreat in Mount Snow, VT after years of separation due to the pandemic.
December is spent… welcoming several new members to the lab!
Postdoctoral Associate Long Han, interested in studying the structure of the epidermal growth factor receptor and the dynamic process of ligand binding.
Postdoctoral Associate Archer Hamidzadeh, interested in studying the dynamics of ERK-MAPK signaling through the use of FRET microscopy.
Pharmacology graduate student Bowei Deng, interested in characterizing endocytosis and trafficking of EGFR induced by various ligands.
While we say good bye to others.
Congratulations to Hector on his new job as a Temp R&D Associate in Oncology at Regeneron Pharmaceuticals through the Magnit agency. He will be missed!
And another conference for Chrystal!
Dec 3, 2022- Chrystal Starbird attended the joint meeting of the American Society for Cell Biology (ASCB) and the European Molecular Biology Organisation (EMBO) as a Poster judge, Panelist, Poster presenter, and member of the MAC committee for ASCB
Exciting things happening in November!
Annual Biomedical Research Conference for Minoritized Scientists
Nov, 15
Chrystal Starbird attended ABRCMS as a judge and recruiter at the NIGMS booth
While Kahlil Walker presented his poster “A Potential Mechanism Through Which Mutations in the Extracellular Domain ErbB2 Function as Drivers of Cancer”.
New Paper out in Nature Communications!
Nov 10, 2022
Great collaboration with Politi and Goldberg groups. Congratulations Iris, David, Kumar, and Yuko! https://www.nature.com/articles/s41467-022-34398-z
EMBO Workshop: Wnt 2022
Nov 15
Post Doctoral Fellow Anselm Sommer presented our work on Wnt-RTK specificity at the EMBO meeting in Japan
Congrats to Zarita for winning the poster prize at the Yale Pharmacology Retreat, Sept. 2022!
A warm welcome to Hector Rivera!
Aug 15, 2022- Read the full interview here https://westcampus.yale.edu/news/meet-undergrads-west-campus-hector-rivera
July 19, 2022
Lab (most of it) at the lake, YCBI 'boats, balls, beer, and BBQ'.
Excited to share that Dr. Chrystal Starbird, from the Ferguson Lab, will be starting her own lab in the Department of Biochemistry and Biophysics at the University of North Carolina at Chapel Hill in February of 2023!
May 16, 2022
A Review from Josh Sheetz and Mark Lemmon title “Looking lively: emerging principles of pseudokinase signaling”
Congrats to Chrystal once again!
Our biggest congratulations to Chrystal Starbird for receiving a prestigious K99/R00 postdoctoral transition award through the Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) program funded by the National Institutes of Health. Read the West Campus press release here!
Chun’s work on GBM mutations in EGFR and their impact on ligand discrimination online in Nature!
February 9, 2022 Read the Yale Cancer Center press release here!
Flurry of preprints from the lab posted on BioRvix!
Check out Courtney’s preprint on the impact of PS binding on TIM-3 signaling!
Check out Chun’s preprint on how GBM mutations alter EGFR signaling through its distinct ligands!
Check out Fumin’s preprint featuring structures of extracellular Wnt-binding modules of RTKs!
Latest Science & Institute News
Congratulations to Chrystal!
January 18th, 2021
Congratulations to Chrystal, who was awarded the Rising Black Scientist Award by Cell Press and Cell Signaling Technology! We are proud to have you as a key part of the lab, and we look forward to reading your essay in next month’s issue of Cell!
Read Chrystal’s essay here!
Congratulations to Krishna!
January 5th, 2021
Congratulations Krishna on receiving a Pathway to Independence Award for Outstanding Early Stage Postdoctoral Researchers from the National Cancer Institute!
We’ll celebrate properly once we can socialize in person once again!